Liquid chromatography of polymer mixtures applying a combination of exclusion and full adsorption mechanisms. 5. Six-component blends of chemically similar polymers

The separation of six-component blends of chemically similar homopolymers utilising the full adsorption-desorption (FAD) process is presented. The main advantage of the FAD approach over other methods represents the successive and independent size- exclusion chromatography (SEC) characterisation of all blend components. The method is based on the full adsorption and retention of all n or n−1 components of the polymer blend from an adsorption promoting liquid (ADSORLI) in a small FAD column. Nonadsorbed macromolecules are forwarded directly into SEC for molecular characterisation. Next, appropriate displacers are successively applied to the FAD column to selectively release preadsorbed blend constituents into the on-line SEC column. Dynamic integral desorption isotherms for single constituents, as well as for polymer blends to be analysed, allow identification of optimal displacer compositions to release just one kind of macromolecule. Model polymer blends containing polystyrene (PS), poly(lauryl methacrylate), poly(butyl methacrylate), poly(ethyl methacrylate), poly(methyl methacrylate) and poly(ethylene oxide) (PEO) or, alternatively, PS, poly(2-ethylhexyl acrylate), poly(butyl acrylate), poly(ethyl acrylate), poly(methyl acrylate) and PEO of similar molar masses can be separated and characterised in one multistep run using nonporous silica FAD packing, toluene as an ADSORLI and its mixtures with a desorption promoting liquid such as ethyl acetate, tetrahydrofuran or dimetylformamide to form displacers with appropriate desorption strength. Received: 9 September 1998 Accepted in revised form: 16 November 1998