| Abstract: | Two novel types of fluorocarbon phospholipids were prepared with choline and phosphate as the polar head group respectively. They form liposomes under dispersion either by sonication or injection. The size of the liposome with choline group is in the range of 32–37 nm based on the measurements of electron microscopy and of dynamic light scattering. However, the light scattering result showed that the size of the liposome containing phosphate group is larger and increases with the increasing pH value of the system. The fluorocarbon liposome is a much lucid dispersion. It is similar to the conventional hydrocarbon analogues in the ability to incorporate the water-soluble substrates. There is a transition point at 53 °C in the plot of fluorescene intensity of the fluorecent probe ANS incorporated into the fluorocarbon liposome versus temperature. |
