Enantioselective Linchpin Catalysis by SOMO Catalysis: An Approach to the Asymmetric α‐Chlorination of Aldehydes and Terminal Epoxide Formation期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Enantioselective Linchpin Catalysis by SOMO Catalysis: An Approach to the Asymmetric α‐Chlorination of Aldehydes and Terminal Epoxide Formation

Authors:	Muriel Amatore Dr. Teresa D. Beeson Sean P. Brown David W. C. MacMillan Prof.

Affiliation:	Merck Center for Catalysis at Princeton University, Washington Road, Princeton NJ 08544‐1009 (USA), Fax: (+1)?609‐258‐5922 http://www.princeton.edu/～dmacgr/

Abstract:	Time for SOme MOre : For the first time SOMO (singly occupied molecular orbital) activation has been exploited to allow a new approach to the α‐chlorination of aldehydes. This transformation can be readily implemented as part of a linchpin catalysis approach to the enantioselective production of terminal epoxides.

Keywords:	epoxidation enantioselectivity asymmetric catalysis organocatalysis