1. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871 (China), Fax: (+86)?10‐6275‐1708;2. Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Environmental Science, Nanjing Normal University, Nanjing, 210097 (China)
Abstract:
Which form to take? The interconversion between the G‐quadruplex and duplex DNA forms in the bcl‐2 promoter could be induced by fluctuations in the pH value or DNA and NH4+ concentrations, by adding CH3OH, and by introducing small molecules (cationic porphyrin and dehydrocorydaline; see scheme).