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Fmoc Solid‐Phase Synthesis of C‐Terminal Peptide Thioesters by Formation of a Backbone Pyroglutamyl Imide Moiety
Authors:A. Pernille Tofteng Dr.  Kasper K. Sørensen  Kilian W. Conde‐Frieboes Dr.  Thomas Hoeg‐Jensen Dr.  Knud J. Jensen Prof. Dr.
Affiliation:1. IGM, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg (Denmark), Fax: (+45)?35‐33‐23‐98;2. Diabetes Protein and Peptide Chemistry, Novo Nordisk Park D6.1.142, 2760 Maaloev (Denmark)
Abstract:
Keywords:amide activation  nucleophilic substitution  peptides  solid‐phase synthesis  thioesters
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