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Deprotonation of the Asp1?Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid‐β Peptide near Physiological pH |
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| Authors: | Christelle Hureau Dr Yannick Coppel Dr Pierre Dorlet Dr Pier Lorenzo Solari Dr Stéphanie Sayen Dr Emmanuel Guillon Prof Dr Laurent Sabater Dr Peter Faller Prof Dr |
| Institution: | 1. CNRS;2. LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, 31077 Toulouse (France);3. Université de Toulouse;4. UPS, INPT;5. LCC, 31077 Toulouse (France), Fax: (+33)?5‐6155‐3003;6. CNRS, Laboratoire du Stress Oxydant et Détoxication, 91191 Gif‐sur‐Yvette (France);7. CEA, iBiTec‐S, SB2SM, 91191 Gif‐sur‐Yvette (France);8. Synchrotron SOLEIL, 91192 Gif‐sur‐Yvette (France);9. Institut de Chimie Moléculaire de Reims (France) |
| Abstract: | |
| Keywords: | amyloid β ‐peptides binding sites copper deprotonation NMR spectroscopy |