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Asymmetric Mannich Reaction of Fluorinated Ketoesters with a Tryptophan‐Derived Bifunctional Thiourea Catalyst
Authors:Xiao Han  Jacek Kwiatkowski  Feng Xue Prof Dr  Kuo‐Wei Huang Prof Dr  Yixin Lu Prof Dr
Institution:1. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore), Fax: (+65)?6779‐1691;2. NUS Graduate School for Integrative Sciences and Engineering (Singapore);3. Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore (Singapore)
Abstract:
Keywords:asymmetric synthesis  fluorination  Mannich reaction  organocatalysis  quaternary stereocenters
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