Departamento de Química Orgánica, Facultad de Química, Universidad de Santiago, 15782 Santiago de Compostela (Spain), Fax: (+34)?981‐595012
Abstract:
Taxing taxanes : A new method for the preparation of alk‐2‐ene‐1,4‐diols from 1,3‐dienes, especially for geometrical constrained derivatives, via dioxirane derivative formation followed by TiIII‐induced oxirane ring opening, is described. The strategy has been very efficiently implemented to the construction of the 11‐ene‐10,13‐diol moiety present in taxol derivatives.
