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Encapsulation and Sustained Release of Curcumin using Superparamagnetic Silica Reservoirs
Authors:Suk Fun Chin  K. Swaminathan Iyer Dr.  Martin Saunders Prof.  Tim G. St. Pierre Prof.  Craig Buckley Prof.  Mark Paskevicius  Colin L. Raston Prof.
Affiliation:1. Centre for Strategic Nano‐Fabrication, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009 (Australia), Fax: (+61)?86488‐8683;2. Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Crawley, WA 6009 (Australia);3. Centre for Strategic Nano‐Fabrication, School of Physics, The University of Western Australia, Crawley WA 6009 (Australia);4. Department of Imaging and Applied Physics, Curtin University of Technology, PO Box U1987, Perth, Western Australia, WA 6845 (Australia)
Abstract:For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe3O4 particles surrounded by a silica matrix.
image

Keywords:curcumin  drug delivery  silica capsule  superparamagnetics  sustained release
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