Institut für Organische Chemie der RWTH Aachen University, Landoltweg 1, 52056 Aachen (Germany), Fax: (+49)?241‐8092391
Abstract:
In control : A new catalytic vinylogous Mukaiyama aldol reaction provides products with high diastereo‐ and enantioselectivities (up to 99 % de and ee; see scheme). The relative and absolute stereochemistry of a representative product was rigorously assigned by NMR and CD spectroscopies (measured and calculated), X‐ray diffraction, and quantum‐chemical calculations.