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Hindered Ureas as Masked Isocyanates: Facile Carbamoylation of Nucleophiles under Neutral Conditions
Authors:Marc Hutchby  Chris E. Houlden Dr.  J. Gair Ford Dr.  Simon N. G. Tyler Dr.  Michel R. Gagné Prof. Dr.  Guy C. Lloyd‐Jones Prof. Dr.  Kevin I. Booker‐Milburn Prof. Dr.
Affiliation:1. School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS (UK), Fax: (+44)?117‐929‐8611;2. AstraZeneca PR&D, Silk Road, Macclesfield, Cheshire, SK10 2NA (UK);3. AstraZeneca, Global Process R&D, Severn Road, Hallen, Bristol, BS10 7ZE (UK);4. Department of Chemistry, Caudill and Kenan Laboratories, UNC‐Chapel Hill, NC 27599‐3290 (USA)
Abstract:
Keywords:carbamoylation  isocyanates  reaction mechanisms  proton switch  urea solvolysis
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