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Synthesis of Indoles through Highly Efficient Cascade Reactions of Sulfur Ylides and N-(ortho-Chloromethyl)aryl Amides |
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| Authors: | Qing-Qing Yang Cong Xiao Liang-Qiu Lu Jing An Fen Tan Bin-Jie Li Wen-Jing Xiao |
| Affiliation: | Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079 (China). |
| Abstract: | Batting the ylides: A simple procedure carried out under mild conditions allows the direct and efficient synthesis of structurally diverse indoles. This approach involves a cascade reaction of sulfur ylides and N-(ortho-chloromethyl)aryl amides. |
| Keywords: | cascade reaction indoles nitrogen heterocycles sulfur ylides |
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