| Abstract: | The fragmentation under eletron impact of some new 2-phenyl-4-acetyl-thiazoles has been studied. The compounds investigaed exhibit molecular ion peaks. Substituents in the para position of the bensene ring do not influence the fragmentation patterns but only the relative abundances of the molecular ion and some fragment ions. However, by introdicing CI and Br in position 5 of the thiazole some signifiecant differences appear (‘ortho effect’). A rearrangement also occurs involving a 5-membered cyclic transition state. Intense doubly charged ions are obseved a fact which is attributed to the presence of two easily ionizable centres. |
