The colleflaccinosides, two chiral bianthraquinone glycosides with antitumor activity from the lichen Collema flaccidum collected in Israel and Russia |
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Authors: | Rezanka Tomás Dembitsky Valery M |
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Institution: | Institute of Microbiology, Czech Academy of Sciences, Vídenská 1083, 142 20 Prague, Czech Republic. rezanka@biomed.cas.cz |
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Abstract: | Colleflaccinosides A and B, two chiral bianthraquinone glycosides from the two geographical varieties of lichen Collema flaccidum collected in Russia and Israel have been isolated as new natural products. Their structures were elucidated using UV, CD, IR, MS, 1D and 2D NMR spectral data, and chemical degradation. The colleflaccinosides B had significant antitumor activity in the crown gall tumor inhibition test. |
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