Synthesis and Crystal Structure Analysis of 5?-O-Tosyl-2,3?-anhydrothymidine

In this paper, 5?-O-tosyl-2,3?-anhydrothymidine has been synthesized and its crystal structure was analyzed. The crystal belongs to the triclinic system, space group P1, with a = 5.397(2), b = 6.1886(18), c = 3.507(5) ?, α ?= 87.74(2), β ?= 89.84(4), γ ?= 73.79(2)°, C17H18N2O6S, Mr = 378.39, Z = 1, V = 432.8(3) ?3, Dc = 1.452 g/cm3, F(000) = 198 and Flack = -0.11(14). No intermolecular hydrogen bonds exist in the crystal, and the angle between benzene ring and pyrimidine planes is 32.23°.