| Rhodium-catalyzed Asymmetric Ring Opening Reaction of Oxabenzo-norbornadiene with Substituted Phenolic Nucleophiles |
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| 作者姓名： | Ying Feng HAN Ding Qiao YANG Er Chang LIU Jian Xia DONG |
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| 作者单位： | Ying Feng HAN，Ding Qiao YANG?，Er Chang LIU，Jian Xia DONG College of Chemistry and Environment，South China Normal University，Guangzhou 510006 |
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| 基金项目： | We would like to thank the Natural Science Foundation of Guangdong Province for financial support （No.04010404）. |
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| 摘 要： | Among the myriad of molecular architectures present in pharmacological agents, certain structures emerge with a higher frequency than others. Among these “privileged structures” is the hydronaphthalene skeleton which can be found in a wide range of comp…
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| 关 键 词： | 不对称开环反应 铑催化剂 氧杂苯降莰烷二烯 酚 亲核试剂 取代反应 |
| 收稿时间： | 2005-07-07 |
Rhodium-catalyzed Asymmetric Ring Opening Reaction of Oxabenzo-norbornadiene with Substituted Phenolic Nucleophiles |
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| Ying Feng HAN Ding Qiao YANG Er Chang LIU Jian Xia DONG.Rhodium-catalyzed Asymmetric Ring Opening Reaction of Oxabenzo-norbornadiene with Substituted Phenolic Nucleophiles[J].Chinese Chemical Letters,2006,17(3):296-298. |
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| Authors: | Ying Feng HAN Ding Qiao YANG Er Chang LIU Jian Xia DONG |
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| Abstract: | We have developed an asymmetric ring opening reaction of oxabenzonorbornadienes with substituted phenolic nucleophiles. Under the reaction conditions ( Rh(COD)Cl]2 (1 mol%), (S)-(R)-PPF-PtBu2 (2 mol%), THF, reflux), the reaction products were obtained with high yield and enantiomeric excesses ( up to 99% ee). |
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| Keywords: | Asymmetric ring opening rhodium-catalyzed oxabenzonorbornadienes |
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