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Surgical effects on soft tissue produced by a 405-nm violet diode laser in vivo |
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| Authors: | Miyazaki H. Kato J. Kawai S. Hatayama H. Uchida K. Otsuki M. Tagami J. Yokoo S. |
| Affiliation: | 1.Department of Stomatology and Oral Surgery, Gunma University Graduate School of Medicine 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan ;2.Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan ;3.Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 161-8655, Japan ;4.Optical Communications R&D Laboratories, Sumitomo Electric Industries, Ltd., 1 Taya-cho, Sakae-ku, Yokohama, 244-8588, Japan ;5.Laboratory of Information Biology, Graduate School of Information Sciences, Tohoku University, 6-3-09, Aramaki-aza, Aoba, Sendai, 980-8579, Japan ; |
| Abstract: | This study evaluated the surgical performance of a 405-nm diode laser in vivo, using living rat liver tissue. Tissue was incised by irradiation with the laser at low output power ranging from 1 W (722 W/cm2) to 3 W (2165 W/cm2) on a manual control at a rate of 1 mm/s. As a control, incisions using a stainless scalpel were compared. Immediately after operation, the surface of the incisions was macroscopically observed and histopathologically evaluated by microscopy. Laser-ablated liver tissue was smooth with observable signs of remnant carbonization and easily acquired hemostasis. The thickness of the denatured layer increased in proportion to the output power; the coagulation layer did not thicken accordingly. Bleeding could not be stopped for tissues incised with the stainless scalpel. The 405-nm diode laser thus proved to be effective for ablating soft tissue with high hemostatic ability at low power. |
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