| 高效液相色谱法同时测定六种二氢吡啶类钙拮抗剂血药浓度 |
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| 引用本文： | 张淑慧,甄耀儒,张立常,李少兵.高效液相色谱法同时测定六种二氢吡啶类钙拮抗剂血药浓度[J].色谱,1995,13(2):132-133. |
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| 作者姓名： | 张淑慧 甄耀儒 张立常 李少兵 |
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| 作者单位： | 河北省人民医院 |
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| 摘 要： | This paper presents the use of an HPLC method to assay nifedipine,nitrendipine,nimoldipine,nisoldip-ine,felodipine, m-nisoldipine concentration in human plasma simultaneously。 Separation was obtained using ODS column and mobile phase of acetonitrile-water(60:40,V/V)with flow rateof 1 mL/min。They were monitored with UV detector at 238 nm,The retention times for 6 drugs mentionedabove were 5.08,7.50,8.57,10.0,11. 91 and 12. 95 min,respectively。The recoveries were all 97%。
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| 关 键 词： | 二氢吡啶类钙拮抗剂 费乐地平 高效液相色谱 尼莫地平 尼群地平 尼索地平 硝苯地平 血浆 |
Simultaneous Determination of 6 Different Dihydropyridines Calcium Antagonists in Human Plasma by High Performance Liquid Chromatography(HPLC) |
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| Zhang Shuhui,Zhen Yaoru, Zhang Lichang and Li Sliaobing.Simultaneous Determination of 6 Different Dihydropyridines Calcium Antagonists in Human Plasma by High Performance Liquid Chromatography(HPLC)[J].Chinese Journal of Chromatography,1995,13(2):132-133. |
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| Authors: | Zhang Shuhui Zhen Yaoru Zhang Lichang and Li Sliaobing |
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| Abstract: | |
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| Keywords: | high performance liquid chromatography dihydropyridines calcium antagonists nifedipine nitrendipine nimoldipine nisoldipine felodipine plasma |
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