Cu(II)-氨基酸-核苷酸三元配合物 II: Cu(II)-L-组氨酸、L-赖氨酸－5'-嘌呤核苷酸三元配合物

合成和表征了新的三元配合物: Cu(L-His)(5'-AMP)]Cl2.4H2O,Cu(L-His)(5'-GMP)]Cl2, Cu(L-His)(5'-IMP)]Cl2.2H2O,Cu(l-Lys)2(5'-GMP)]Cl2.6H2O, Na2Cu(L-Lys)2(5'-GMPH_2)].6H2O,Na2Cu(L-Lys)2(5'-GTPH_2)].6H2O, Na2Cu(L-Lys)2(5'-IMPH_2)].10H2O. IR及NMR谱表明, 5'-嘌呤核苷酸以嘌呤碱基上的7-N原子与Cu(II)配位。在5'-嘌呤核苷酸形成的配合物中, 磷酸根不参与配位, 但是Na2.5'-GMPH-2和Na.5'-GTPH-2的磷酸根参与配位, 而Na2.5'-IMPH-2的磷酸根不参与配位。

Ternary complexes of copper(II) with amino acid and nucleotide

The ternary complexes of copper(II) with amino acid (L-His and L-Lys) and nucleotide (5'-purine nucleotide and its salt of sodium) were first synthesized and characterized by elemental, conductivity, IR, ^1H NMR and ^1^3C NMR spectra. In the ternary complexes, the purine base coordinates with copper(II) through the 7-N atom. The phosphate group of 5'-nucleotide in the ternary complexes does not coordinate with copper(II). When the nucleotide takes part in the reaction in the form of Na2.5'-GMPH_2 and Na2.5'-GTPH_2, the phosphate group may be coordinate with copper(II) in the ternary complexes, but not for Na2.5'-IMPH_2.