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An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives |
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| Authors: | Duan Shu-Wen Li Yang Liu Yi-Yin Zou You-Quan Shi De-Qing Xiao Wen-Jing |
| Institution: | Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China. |
| Abstract: | An efficient organocatalytic Michael-aldol cascade reaction for the asymmetric synthesis of spirocyclic oxindole derivatives fused with tetrahydrothiophenes has been developed through a formal 3+2] annulation strategy. |
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