Total synthesis of the terpenoid buddledone A: 11-membered ring-closing metathesis |
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Authors: | Cai Zhengxin Yongpruksa Nattawut Harmata Michael |
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Affiliation: | Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA. |
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Abstract: | The first total synthesis of buddledone A was accomplished in seven steps from methyl ethyl ketone (MEK). The key step in the sequence featured an 11-membered ring formation by ring-closing metathesis. |
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