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The First Specific TiIV–Protein Complex: Potential Relevance to Anticancer Activity of Titanocenes
Authors:Hongzhe Sun  Hongyan Li  Richard A. Weir  Peter J. Sadler
Abstract:The transfer of titanium ions from titanium citrate and titanocene dichloride to the blood plasma protein transferrin was proven unequivocally by UV/Vis and NMR spectroscopy. The results may provide insight intoan important step in the mechanism of action of titanium anticancer drugs.
Keywords:Antitumor agents  Bioinorganic chemistry  Titanium  Transferrin
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