|
|||||
|
|
Acylzirconocene Chloride as an “Unmasked” Acyl Anion |
|
| Authors: | Susumu Harada Takeo Taguchi Nobuhito Tabuchi Kensuke Narita Yuji Hanzawa |
| Abstract: | Under mild conditions the acyl group of acylzirconocene chloride 1 formed from an alkene or alkyne and [(C5H5)2ZrHCl] reacts as an “unmasked” acyl anion. The Lewis acid mediated reactions with aldehydes that yield α-ketol products in high yields demonstrate the versatility of this reagent for C–C coupling. |
| Keywords: | Acylations Aldehydes Lewis acids Nucleophilic additions Zirconium |