New Protecting Group Strategies for the Solid-Phase Synthesis and Modification of Peptides,Oligonucleotides, and Oligosaccharides |
| |
Authors: | Oliver Seitz |
| |
Abstract: | Blocking and activation can be achieved with protecting groups such as the ortho-nitrobenzenesulfonyl group (see picture). In solid-phase peptide synthesis, this group can be used for temporary protection (path A) as well as the activation and selective N-alkylation (path B) of an amino group. |
| |
Keywords: | Carbohydrates Nucleic acids Peptides Protecting groups Solid-phase synthesis |
|
|