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Studies on Interaction of Norfloxacin,Cu2+, and DNA by Spectral Methods
Authors:Gongwu?Song  author-information"  >  author-information__contact u-icon-before"  >  mailto:songgw@hubu.edu.cn"   title="  songgw@hubu.edu.cn"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Qiujun?Yan,Yu?He
Affiliation:(1) Faculty of Chemistry and Material Science, Hubei University, Wuhan, 430062, People's Republic of China
Abstract:The interactions of norfloxacin (NFA), DNA, and Cu2+ are studied by fluorescence and UV-spectra method. According to the experimental results, it can be concluded that NFA can form a steady binary complex with Cu2+. There is a linear relationship between the Fluorescence intensity of the norfloxacin–Cu2+–DNA system and the concentration of DNA. And when the concentration of the NFA is 1.95×10−5 mol L−1, they possess a good linearity in the concentration of DNA ranged from 4.7×10−6 to 2.8×10−5 mol L−1.It is a good method due to the high sensitivity and selectivity.
Keywords:Norfloxacin  DNA  Cu2+  fluorescence  static-quenching style
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