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Anticancer anthrapyrazoles. Improved syntheses of clinical agents CI-937, CI-941, and piroxantrone hydrochloride |
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| Authors: | Vladimir G. Beylin Norman L. Colbry Om P. Goel Jerome E. Haky Donald R. Johnson Judith L. Johnson Gerald D. Kanter Robert L. Leeds Boguslawa Leja Edward P. Lewis Christopher D. Rithner H. D. Hollis Showalter Anthony D. Sercel William R. Turner Susan E. Uhlendorf |
| Abstract: | Improved processes for the synthesis of bulk quantities of the anthrapyrazole clinical agents CI-937, CI-941, and piroxantrone hydrochloride are reported. Reported also are detailed analytical and spectroscopic data for these agents and intermediates of the synthetic sequences. |
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