Chromatographic analysis of phospholipid and cholesterol oxidation |
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Authors: | Krull U J Thompson M Arya A |
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Affiliation: | Chemical Sensors Group, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada. |
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Abstract: | Capillary thin layer and gas chromatographic methods for analysis of the extent of oxidation in phosphatidyl choline/cholesterol samples are described. Examples of systems suitable for qualitative and quantitative analysis, based on use of unmodified samples or of their derivatives, are illustrated. A method for concurrent quantitative determination of phospholipid and sterol without preseparation is introduced and is based on extension of a previous lipid trans-methylation technique. |
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