Cannabinoids,Phenolics, Terpenes and Alkaloids of Cannabis |
| |
| Authors: | Mohamed M Radwan Suman Chandra Shahbaz Gul Mahmoud A ElSohly |
| |
| Institution: | 1.National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA; (M.M.R.); (S.C.);2.ElSohly Laboratories, Inc., 5 Industrial Park Drive, Oxford, MS 38655, USA;3.Sally McDonnell Barksdale Honors College, University of Mississippi, Oxford, MS 38677, USA;4.Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA |
| |
| Abstract: | Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during the early 19th century. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type constituents. More than 500 compounds have been reported from C. sativa, of which 125 cannabinoids have been isolated and/or identified as cannabinoids. Cannabinoids are C21 terpeno-phenolic compounds specific to Cannabis. The non-cannabinoid constituents include: non-cannabinoid phenols, flavonoids, terpenes, alkaloids and others. This review discusses the chemistry of the cannabinoids and major non-cannabinoid constituents (terpenes, non-cannabinoid phenolics, and alkaloids) with special emphasis on their chemical structures, methods of isolation, and identification. |
| |
| Keywords: | Cannabis sativa cannabinoids non-cannabinoid phenols flavonoids terpenes alkaloids |
|
|
