Phenolic compounds from <Emphasis Type="Italic">Clinopodium urticifolium</Emphasis> |
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Authors: | Qiufen Hu Huaixue Mu Haitao Huang Huaying Lv Shuli Li Guangyu Yang |
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Institution: | (1) Key Laboratory of Ethnic Medicine Resource Chemistry (Yunnan University of Nationalities), State Ethnic Affairs Commission and Ministry of Education, Kunming, 650031, P. R. China;(2) Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming, 650106, P. R. China;(3) School of Pharmaceutical Sciences, Peking University, 100191 Beijing, P. R. China; |
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Abstract: | A new phenolic compound, clinopodphenol A (1), together with six known ones, was isolated from the whole plant of Clinopodium urticifolium. The structure of 1 was elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. The anti-HIV-1 activity and cytotoxicity
were evaluated for compound 1. It showed significant potential cytotoxic ability and moderate anti-HIV-1 activity. |
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