The polarographic behavior and determination of glafenine

Glafenine was found to be reducible at the dropping-mercury electrode (DME) in Britton-Robinson buffer (BRB) over the whole pH range. In the alkaline range, a well-defined cathodic wave was produced. The wave was characterized as being diffusion-controlled and partially affected by adsorption phenomena. A method was proposed for the determination of glafenine in tablets and the results obtained were satisfactorily accurate and reproducible.