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3β,6β‐Di­hydroxy­olean‐12‐en‐27‐oic acid: a cytotoxic and apoptosis‐inducing oleanane triterpenoid from the rhizome of Astilbe chinensis
Authors:Hong‐Xiang Sun  Yuan‐Jiang Pan
Abstract:3β,6β‐Di­hydroxy­olean‐12‐en‐27‐oic acid, C30H48O4, a cytotoxic and apoptosis‐inducing oleanane triterpenoid, which was isolated from the rhizome of Astilbe chinensis, consists of a linear array of five fused six‐membered rings. The central ring has a slightly distorted half‐chair conformation, while the four outer rings adopt chair conformations. Two hydroxy groups and one carboxy group serve simultaneously as hydrogen‐bond donors and acceptors, forming molecular chains.
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