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The Glc Separation of Indole Amines and Indole Alcohols as Heptafluorobutyryl Derivatives
Abstract:Abstract

Indole amines and indole alcohols were converted to heptafluoro-butyryl (HFB) derivatives by an acyl transfer reaction with heptafluoro-butyrylimidazole. The indole NH group as well as all amino and hydroxyl groups were acylated. The HFB derivatives have excellent gas chroma-tographic properties and can be used with either hydrogen flame or electron capture detection systems. Mass spectra of the HFB derivatives of biologic N, N-dialkyl indole amines are very characteristic; these compounds can be identified easily by GLC-MS methods.
Keywords:indole amines  indole alcohols  heptafluorobutyramides  serotonin  bufotenin  N  N-dimethyltryptamine  N  N-diethyltryptamine  5-methoxy-N  N-dimethyltryptamine  5-methoxytryptamine  N-methyltryptamine  tryptamine  tryptophol  5-methoxyltryptophol  gas chromatography  mass spectrometry
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