Abstract: | Abstract Computer simulation of electrochemical processes that govern the operation of conducting polymer modified electrodes (CPME) have been reported in this paper. Comparison of the behaviour of a biocatalyst (GOX) in free solution and in the immobilized phase in conducting polymer modified electrodes (CPME) has been provided The output has been obtained using the Runga Kutta numerical method solved by programming in FORTRAN 77. The results point out that the catalytic current generated by an immobilized enzyme in layer is larger as compared to that for the enzyme in solution, and that it varies with the thickness of the diffusion layer. |