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Flow Injection Chemiluminescence Determination of Etamsylate with Electrogenerated Hypochlorite
Abstract:Abstract

A fast and simple electrogenerated unstable reagent chemiluminescence system for flow injection analysis of etamsylate is described, based on a decrease in the chemiluminescence intensity from the luminol-hypochlorite system. The response is linear to the concentration of etamsylate in the range from 1x109 to 8x 10?9. The detection limit is 6 x 10?10 g ml?1. The relative standard deviation is 3.1% at 2 x 10?9 g ml?1 (n=7). The proposed method is suitable for automatic and continuous analysis and has been successfully tested for determination of etamsylate in pharmaceutical formulations.

Keywords:Flow injection  Chemiluminescence  Etamsylate  Luminol  Electrolysis  Pharmaceutical Analysis
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