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Analysis of Urinary Calculi Containing Triamterene. Presence of A Glucuronic Metabolite.
Abstract:Abstract

Urinary calculi containing triamterene were described since 1979. We have studied calculi, obtained from an anuric patient, by surgery. This paper describes the advanced techniques that were used, such as infrared spectroscopy, nuclear magnetic resonance, mass spectrometry associated with thin-layer chromatography or gas chromatography, to show the presence of unusual compounds. Six metabolites are found, among them pure triamterene (96%), hydroxy-triamterene, and a particular metabolite containing glucuronic acid.
Keywords:Calculus  Triamterene  Infrared Spectroscopy  Mass Spectroscopy  Metabolites  Glucuronic Acid
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