| Abstract: | Abstract Noninvasive glucose sensing is an active area of research and development with many different approaches being explored since the 1980s. The promise of this approach is to provide a measure of the blood glucose concentration in a rapid, painless, and cost-effective manner so that people with diabetes can better maintain tight glycemic control, thereby reducing the complications of diabetes. This mini-review covers the major approaches to noninvasive glucose sensing and focuses on issues that must be resolved before a clinically useful device can be developed. A strong emphasis is placed on measurement selectivity, and methods to examine and characterize the selectivity of such a complex analytical problem are discussed. |
