Abstract: | Abstract The reaction between curcumin and boric acid to form the 2:1 complex rosocyanin has hitherto been considered to require an almost water-free solution. It has now been shown that rosocyanin may be formed even if large amounts of water are present, provided that a suitable organic solvent is added. The theoretical conditions for such a solvent have been investigated. Procedures are given where the reaction takes place in a homogeneous solution or possibly at the organic interface. For analytical purposes the rosocyanin formed could either be measured in a homogeneous solution or extracted into an upper or lower organicphase. Methylisobutylketone seems to be the most suitable solvent which possesses convenient analytical properties. |