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Structural Elucidation of the Cu(II)- Streptomycin Complex. Indirect Estimation of Streptomycin by Atomic Absorption Spectroscopy
Abstract:Abstract

The neutral Cu(II) - streptomycin .4 H2O] complex is prepared and characterized by elemental analysis, TGA, IR, electronic and ESR spectra. The bonding between Cu(II) and streptomycin is found to take place through a Cu-O bond. The indirect estimation of streptomycin sulfate by atomic absorption spectroscopy is affected by the addition of an excess of cupric ions in slightly alkaline medium; the unreacted copper is separated as insoluble carbonate. The concentration of streptomycin in its product with copper is then indirectly determined from a pre-drawn caliberation curve for standard copper sulfate solutions.
Keywords:Cu(II)- Streptomycin  atomic absorption  TGA  IR  ESR
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