Click chemistry: a new facile and efficient strategy for preparation of functionalized HPLC packings |
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Authors: | Guo Zhimou Lei Aiwen Liang Xinmiao Xu Qing |
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Institution: | College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China. |
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Abstract: | Click chemistry has been successfully extended into the field of preparation of functionalized HPLC packings, proving a novel facile and efficient strategy for covalently bonding stationary phases onto HPLC grade silica beads; the potential has been demonstrated by the preparation of "Click I-IV" columns and preliminary results in the separation of sugars. |
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