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Bioactive molecular sheets from self-assembly of polymerizable peptides
Authors:Moon Kyung-Soo  Lee Eunji  Lim Yong-beom  Lee Myongsoo
Affiliation:Center for Supramolecular Nano-Assembly, Department of Chemistry, Yonsei University, Shinchon 134, Seoul 120-749, Korea. mslee@yonsei.ac.kr.
Abstract:We have demonstrated that polymerizable peptides self-assemble into a unique sheet-like 2D structure in bulk solution that can be covalently fixed to produce 2D molecular objects which were shown to be efficient at delivering cargos into living cells and are nearly nontoxic in contrast to non-polymerized nanostructures.
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