Compact,broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region |
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Authors: | Bizheva K Povazay B Hermann B Sattmann H Drexler W Mei M Holzwarth R Hoelzenbein T Wacheck V Pehamberger H |
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Institution: | Department of Medical Physics, Christian Doppler Laboratory, University of Vienna, Waehringer Strasse 13, Vienna, Austria. |
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Abstract: | A novel, compact, user friendly fiber laser with a broad emission bandwidth (MenloSystems, lambdac = 1375 nm, deltalambda = 470 nm, Pout = 4 mW) was used to achieve unprecedented sub-2-microm axial resolution optical coherence tomography (OCT) in nontransparent biological tissue in the 1300-nm wavelength region. Fresh human skin and arterial biopsies were imaged ex vivo with approximately 1.4-microm axial and approximately 3-microm lateral resolution and 95-dB sensitivity, demonstrating the great potential for clinical OCT applications of this stable, low-cost, and turn-on-key fiber laser. |
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