Synthesis of Dehydro Derivatives of Cycloheximide and Inactone |
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| Authors: | T N Buravskaya and F A Lakhvich |
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| Institution: | (1) National Academy of Sciences of Belarus, Institute of Bioorganic Chemistry, ul. Akad. Kuprevicha 5, korp. 2, Minsk, 220141, Belarus |
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| Abstract: | Catalytic hydrogenation of 3-chloro-2-(2,6-dioxopiperidin- 4-ylacetyl)-2-cyclohexenones over palladium catalyst leads to formation of dehydrocycloheximide derivatives. Reduction of the same compounds with Zn-Ag yields dehydroinactone derivatives. |
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