Recent applications of quantitative nuclear magnetic resonance spectroscopy in pharmaceutical research |
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Authors: | Rackham D M |
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Affiliation: | Lilly Research Centre Limited, Erl Wood Manor, Windlesham, Surrey, GU20 6PH, England. |
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Abstract: | Increasing use is being made of N.M.R. spectroscopy as a quantitative analytical tool. Recent developments (1970-mid-1975) in methods and reagents are discussed with special regard to the role of Fourier-transform spectrometers, lanthanide-shift reagents and the choice of standard materials. Applications to quantitative analytical problems in pharmaceutical research are listed together with an indication of the advantages of the N.M.R. method over official analytical procedures. |
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