Fluorescence-based detection of single nucleotide permutation in DNA via catalytically templated reaction |
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| Authors: | Pianowski Zbigniew L Winssinger Nicolas |
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| Affiliation: | Laboratoire de Chimie Organique et Bioorganique, Institut de Science et d'Ingénierie Supramoléculaires, Université Louis Pasteur-CNRS, 8 allée Gaspard Monge, 67083 Strasbourg, France. |
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| Abstract: | Templated reduction of low fluorescence azidocoumarin-PNA conjugate to high fluorescence aminocoumarin was achieved using a catalytic amount of DNA with single nucleotide resolution. |
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