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Development of radiation medicine at DLNP, JINR |
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| Authors: | E M Syresin A V Agapov N V Anfimov G A Chelkov V N Gaevsky V G Elkin G A Karamysheva M Yu Kazarinov N N Khovansky S A Kostromin V G Kruchonok Z V Krumshtein E I Luchin G V Mitsyn A G Molokanov N A Morozov A G Olshevsky V M Romanov Z Ya Sadygov E V Samsonov A S Selyunin N G Shakun K N Shipulin G D Shirkov S V Shvidky A S Zhemchugov V A Novikov O P Tolbanov A V Tyazhev Y Jongen |
| Institution: | 1. Joint Institute for Nuclear Research, Dubna, Russia 2. Academician V.D. Kouznetsov Siberian Physical and Technical Institute, Tomsk State University, Tomsk, Russia 3. Ion Beam Application, Louvain-la-Neuve, Belgium |
| Abstract: | The Dzhelepov Laboratory of Nuclear Problems’ activity is aimed at developing three directions in radiation medicine: 3D conformal proton therapy, accelerator techniques for proton and carbon treatment of tumors, and new types of detector systems for spectrometric computed tomography (CT) and positron emission tomography (PET). JINR and IBA have developed and constructed the medical proton cyclotron C235-V3. At present, all basic cyclotron systems have been built. We plan to assemble this cyclotron at JINR in 2011 and perform tests with the extracted proton beam in 2012. A superconducting isochronous cyclotron C400 has been designed by the IBA-JINR collaboration. This cyclotron will be used for radiotherapy with proton, helium and carbon ions. The 12C6+ and 4He2+ ions will be accelerated to an energy of 400 MeV/amu, the protons will be extracted at the energy 265 MeV. The construction of the C400 cyclotron was started in 2010 within the framework of the Archarde project (France). Development of spectrometric CT tomographs may allow one to determine the chemical composition of a substance together with the density, measured using traditional CT. This may advance modern diagnostic methods significantly. JINR develops fundamentally new pixel detector systems for spectrometric CT. The time-of-flight (TOF) system installed in the positron emission tomograph (PET) permits essential reduction in the detector noise from occasional events of different positron annihilations. The micropixel avalanche photodiodes (MAPDs) developed at JINR allow a factor of 1.5 reduction in the resolution time for the PET TOF system and suppression of the noise level as compared to commercial PET. The development of a combined PET/MRI is of considerable medical interest, but it cannot be made with the existing PET tomographs based on detectors of compact photomultipliers due to strong alternating magnetic field of MRI. Change-over to detectors of micropixel avalanche photodiodes permits making a combined PET/MRI. |
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