Intramolecular hydroamination catalysed by Ag complexes stabilised in situ by bidentate ligands |
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| Authors: | Sophie R Beeren |
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| Institution: | School of Chemistry, The University of New South Wales, NSW, Australia |
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| Abstract: | A series of silver complexes generated in situ from AgOSO2CF3 (AgOTf) and a range of bidentate ligands were investigated as catalysts for the intramolecular hydroamination of 4-pentyn-1-amine. A variety of P- and N-donor ligands were tested including the novel pyrazole-phosphine ligand 1-(2-(diphenylphosphino)phenyl)pyrazole. The best catalyst was formed from equimolar amounts of the P,N-donor ligand 1-(2-(diphenylphosphino)ethyl)pyrazole and AgOTf, which achieved a turnover rate of 129 h−1 for the cyclisation of 4-pentyn-1-amine. |
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| Keywords: | Hydroamination Silver catalyst Bidentate ligand Alkynylamine Triflate Cyclisation |
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