A facile and expeditious microwave-assisted synthesis of 4-aryl-2-ferrocenyl-quinoline derivatives via multi-component reaction |
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| Authors: | Shu-Jiang Tu Shu Yan Xu-Dong Cao Shan-Shan Wu Xiao-Hong Zhang Wen-Juan Hao Zheng-Guo Han Feng Shi |
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| Affiliation: | College of Chemistry and Chemical Engineering, Xuzhou Normal University, Key Laboratory of Biotechnology for medicinal Plant, Xuzhou, Jiangsu 221116, PR China |
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| Abstract: | An efficient and rapid route for the synthesis of 4-aryl-2-ferrocenyl-quinoline derivatives through microwave-assisted multi-component reaction of acetylferrocene with aromatic aldehyde and dimedone in the presence of ammonium acetate using DMF as reaction media at 100 °C is described. This novel procedure lends itself well to combinatorial methods, providing the target heteropolymetallic compounds in excellent yield without further purification. |
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| Keywords: | Ferrocene Heteropolymetallic compound 4-Aryl-2-ferrocenyl-quinoline Multi-component reaction |
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