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Fibre-fluorescence immunosensor based on evanescent wave detection
Authors:R.G. Eenink  H.E. de Bruijn  R.P.H. Kooyman  J. Greve
Affiliation:Department of Applied Physics, University of Twente, P.O. Box 217, 7500 AE Enschede The Netherlands
Abstract:A fibre-optic sensor capable of detecting an immune reaction between fluorescently labelled antigens and antibodies bound at the waveguide surface is described. In a configuration where skew rays were detected, a signal level was found that made detection of a concentration of 10?9 M antigen possible.
Keywords:Fibre-optic sensor  Immune reactions
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