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肿瘤坏死因子(TNF)的分子结构和生物学活性
引用本文:王良斌,侯水薇,吴文鹃.肿瘤坏死因子(TNF)的分子结构和生物学活性[J].新疆师范大学学报(自然科学版),1994(2).
作者姓名:王良斌  侯水薇  吴文鹃
作者单位:新疆师范大学生物系(王良斌,侯水薇),上海生物制品研究所(吴文鹃)
摘    要:TNF最初被发现是因为它显示了抗癌活性,现已判定它是免疫细胞接受某些特定的刺激因子所产生的多功能细胞因子,它参与了炎症和免疫反应以及细胞生长或抑制的各种蛋白质因子中的一族,本文讨论了TNF的分子结构和生物学活性及两者之间的关系。

关 键 词:TNF  LPS  恶性肿瘤  炎症和免疫反应

MOLECULAR STRUCTURE AND BIOLOGICAL ACTIVITY OF THE TUMOR NECROSIS FACTOR (TNF)
Wang Liangbin,Hou Shuiwei,Wu Wenjuan.MOLECULAR STRUCTURE AND BIOLOGICAL ACTIVITY OF THE TUMOR NECROSIS FACTOR (TNF)[J].Journal of Xinjiang Normal University(Natural Sciences Edition),1994(2).
Authors:Wang Liangbin  Hou Shuiwei  Wu Wenjuan
Institution:Wang Liangbin Hou Shuiwei Wu Wenjuan
Abstract:TNF were initial discovered just because they showed anticarcinogenic activity. Now they have been identified as multi-function cytokine produced by immunocytes which are stimulated by specific factor. In addition, TNF partipate in inflammatory and immune re-sponses, and consist of one family of variety of protein factor, relate to cell growth or sup-pression. This paper discusses TNF's molecular structure and their biological activities and relations between both.
Keywords:LPS  Inflammatory and immune responses  Maligmancy  
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