Intramolecular cyclization of 1-(2-arylethyl)tetrahydro-6-hydroxy-1H-pyrimidin-2-thiones: effect of substituents on reactivity |
| |
Authors: | Alexander S Fisuyk Aleksey Y Mukanov and Nikolay V Poendaev |
| |
Institution: | (1) Department of Pharmaceutical Sciences, Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, NC 27707, USA |
| |
Abstract: | Convenient synthetic procedures for 1,2,3,6,7, 11b-hexahydro-4H-pyrimido6, 1 -a] isoquinolin-4-thiones and 2,3,6,7,12,12b-hexahydro-1H-pyrimido1′,6′:1,2]pyrido3,4-b]indole-4-thiones have been developed. Structural factors which influence on a cascade cyclization process have been elucidated. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|